Light or moderate alcohol consumption might also have a beneficial effect on mortality from diabetes mellitus and nephritis, nephrotic syndrome, or nephrosis. Infrequent, light, and moderate alcohol consumption were inversely associated with mortality from all causes, CVD, chronic lower respiratory tract diseases, Alzheimer’s disease, and influenza and pneumonia. Furthermore, binge drinking ≥ 1 day/week was associated with a higher risk of mortality from all causes (1.15 1.09 to 1.22), cancer (1.22 1.10 to 1.35), and accidents (unintentional injuries) (1.39 1.11 to 1.74). In contrast, heavy drinkers had a significantly higher risk of mortality from all causes, cancer, and accidents (unintentional injuries). Also, light or moderate drinkers were associated with lower risk of mortality from diabetes mellitus and nephritis, nephrotic syndrome, or nephrosis. Compared with lifetime abstainers, current infrequent, light, or moderate drinkers were at a lower risk of mortality from all causes, CVD, chronic lower respiratory tract diseases, Alzheimer’s disease, and influenza and pneumonia. Resultsĭuring an average follow-up of 12.65 years, among the 918,529 participants (mean age 46.1 years 48.0% male), 141,512 adults died from all causes, 43,979 from cardiovascular disease (CVD), 33,222 from cancer, 8246 from chronic lower respiratory tract diseases, 5572 from accidents (unintentional injuries), 4776 from Alzheimer’s disease, 4845 from diabetes mellitus, 2815 from influenza and pneumonia, and 2692 from nephritis, nephrotic syndrome, or nephrosis. The main outcome was all-cause and cause-specific mortality. Self-reported alcohol consumption was categorized into seven groups (lifetime abstainers former infrequent or regular drinkers and current infrequent, light, moderate, or heavy drinkers). This was a population-based cohort study of adults aged 18 years or older in the National Health Interview Survey (1997 to 2014) with linkage to the National Death Index records through December 31, 2019. Therefore, this study sought to examine the prospective association of alcohol consumption with all-cause and cause-specific mortality in the US population. Previous studies have shown inconsistent findings regarding the association of light to moderate alcohol consumption with cause-specific mortality.
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